Too Old to Operate1h
More micrometastases, more recurrence? The role of qPCR of PSA mRNA in lymph nodes during prostatectomy.
Radical prostatectomy is a standard treatment for prostate cancer, yet about 30% of patients experience rising biochemical markers within a decade post-surgery. Pelvic lymph node sampling during ...
Too Old to Operate1h
Ecodevelopmental influences on latent classes of substance use among urban American Indian adolescents.
The large majority (over 70%) of American Indian adolescents who reside in cities rather than tribal lands or rural areas report relatively earlier onset of substance use and more harmful associated ...
Too Old to Operate1h
Athlete Selective Androgen Receptor Modulators Abuse: A Systematic Review.
Selective androgen receptor modulators (SARMs) are small-molecule compounds that exert agonist and antagonist effects on androgen receptors in a tissue-specific fashion. Because of their ...
Too Old to Operate1h
Demographic and clinical trends of young breast cancer patients from the national cancer database: disproportionate effect on minority populations.
There is an increasing incidence of young breast cancer (YBC) patients with uncertainty surrounding the factors and patterns that are contributing.We obtained characteristics and survival data from ...
Too Old to Operate1h
The implication of pericardial effusion in the third trimester for preeclampsia and heart failure in high-risk pregnant women.
With the growing number of high-risk pregnant women, echocardiography frequently reveals pericardial effusion (PE). However, the clinical implications of PE are unknown.We analyzed a cohort of 406 ...
Too Old to Operate1h
Genetic predisposition of metabolic dysfunction-associated steatotic liver disease: a population-based genome-wide association study.
Although metabolic dysfunction-associated steatotic liver disease (MASLD) has been proposed to replace the diagnosis of non-alcoholic fatty liver disease (NAFLD) with new diagnostic criteria since ...
Too Old to Operate1h
Multigenerational effects of individual and binary mixtures of two commonly used NSAIDs on Daphnia carinata.
Pharmaceuticals, including non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (IBU) and naproxen (NPX), are widely used for medical purposes but have also become prevalent environmental ...
Too Old to Operate2d
Emerging Mezigdomide-Based Options for Heavily Pre-Treated MM
Three novel mezigdomide-based triplet therapies were associated with anti-tumor activity in patients with relapsed or refractory multiple myeloma.
Too Old to Operate2d
ZUMA-5: Curative Potential of Axi-Cel in Follicular Lymphoma
Axicabtagene ciloleucel had durable responses, long-term survival, and consistent outcomes in patients with relapsed or ...
Too Old to Operate2d
Subgroup Analyses of Phase 3 Uproleselan Study in AML Encourages Further Exploration
Interesting trends were observed in the subgroup analyses of the phase 3 uproleselan study in relapsed or refractory acute ...
Too Old to Operate2d
AQUILA: Early Intervention With Daratumumab Extends Survival in High-Risk SMM
Early interventions with daratumumab reduced progression and prolonged overall survival rate in patients with high-risk ...
Too Old to Operate2d
Elevated Biomarkers Throughout Pregnancy Indicate Preeclampsia Risk
Elevations in biomarkers such as uterine artery pulsatility index and placental growth factor throughout pregnancy indicate ...