This is the first time that this signaling pathway (GAS6 and AXL) has been directly implicated in insulin resistance. This ...

BACKGROUND: The docking protein IRS2 (insulin receptor substrate protein-2) is an important mediator of insulin signaling and ...

Dopamine receptors bind dopamine, insulin receptors bind insulin ... a sequence of molecular switches to internal signaling pathways. Membrane receptors fall into three major classes: G-protein ...

Introduction ADVERTISEMENT Peptides have become a focal point in research due to their intricate interactions with metabolic ...

For experiments investigating post-transcriptional regulation, I use the Drosophila insulin-like receptor pathway and the cellular response to insulin. Transcriptional control of gene expression The ...

A study led by Manuel Vázquez Carrera, group leader at the Diabetes and Associated Metabolic Diseases Networking Biomedical ...

G-protein coupled receptors regulate hormone secretions in ... levels that stems from the decreased secretion and/or action of insulin. Two major forms of diabetes exist, type 1 and type 2.

Semaglutide injections effectively support weight loss by regulating appetite and glucose levels, offering benefits for ...

Why insulin ... receptor from its downstream effectors, effectively terminating insulin signal transduction. In short, this means that insulin resistance can disrupt the normal signaling pathways ...

Our previous studies have shown that ProINS-Tf was converted to active insulin-transferrin (INS-Tf) via the transferrin (Tf)-receptor–mediated pathway in hepatoma cells. We hypothesized that ...

An experimental weight-loss pill helped people drop 13% of their body weight in a three-month period. The results from early ...