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Lions vs. 49ers odds, spread, line, time: Week 17 Monday Night Football picks by NFL model on 28-12 roll

SportsLine's model has simulated San Francisco vs. Detroit on Monday Night Football 10,000 times and revealed its MNF picks and NFL predictions

Covers · 7d

Lions vs 49ers Predictions, Picks, and Best Bets for NFL Week 17

Lions vs. 49ers predictions and expert picks for Monday Night Football on December 30. Expect a big night from Jauan Jennings, who's become a focal point for the San Fran offense.

Hosted on MSN · 11d

Lions at 49ers: Predictions, picks, odds for NFL Week 17 game

A rematch of last year's NFC Championship Game, the Detroit Lions vs. San Francisco 49ers was expected to be one of the best games of the season when the schedule was released. Now though, most people could care less about this Monday night matchup.

Lions Secure Top Spot Heading Into Postseason

Hosted on MSN · 5h

NFL Power Rankings: Lions Secure Top Spot Heading Into Postseason

Detroit secured the NFC's top seed by beating Minnesota on Sunday Night Football, but don't count the Vikings out just yet.

USA Today · 7h

Who should Lions want to play in NFL playoffs 2025? Ranking 4 potential opponents

Detroit Lions could play the Rams, Vikings, Commanders or Packers at Ford Field in NFL playoffs divisional round. Here's how we rank them.

U.S. News & World Report · 1d

Lions Secure NFC's No. 1 Seed, Broncos and Buccaneers Clinch the NFL's Final Two Playoff Spots

The Los Angeles Chargers beat Las Vegas to get the No. 5 seed. The Chargers (10-7) will play at Houston (10-7) in the first wild-card game on Saturday afternoon. The Ravens (12-5)

7don MSN

What channel is Lions vs 49ers on tonight? NFL Monday Night Football time, TV schedule

It's the Detroit Lions vs San Francisco 49ers on Monady Night Football in Week 17 of the 2024 NFL season. Here's how to watch ...

6don MSN

Lions Set Impressive NFL Record With Another High-Scoring Game Against 49ers

With the high-scoring contest against the 49ers, the Lions clinched their fifth game this season with 40 points and 0 ...

6don MSN

Lions Make NFL History in Win Over 49ers

The Detroit Lions have two wide receivers and two running backs with more than 1,000 scrimmage yards, the most in NFL history ...

7don MSN

NFL Monday schedule, TV: How to watch Detroit Lions vs San Francisco 49ers game today

What channel is Monday Night Football on? How to watch NFL Week 17 game between Detroit Lions, San Francisco 49ers on TV, ...

20hon MSN

NFL News: Kyle Shanahan makes statement that could reassure 49ers fans heading into 2025 season

After a challenging year leading the San Francisco 49ers, Kyle Shanahan delivered a subtle but reassuring message to fans, signaling optimism for the next season. Kyle Shanahan is well aware of how ...

1don MSN

Detroit Lions' Penei Sewell Injury Update After Earning NFL Pro Bowl Nod

Detroit Lions offensive tackle Penei Sewell has been selected to his third consecutive NFC Pro Bowl roster, but the former Oregon Ducks unanimous All-American s ...

2don MSN

49ers College Teammates Projected for Awesome Achievement in Week 18

Former college teammates Josh Dobbs and Jauan Jennings could pair up to get Jennings his first 1,000 yard season ...

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