It happened just after 6:30 a.m. on southbound lanes near First Street, according to the California Highway Patrol.

The man was driving southbound in the northbound lanes of Interstate 110 when his Honda hit a cargo van, officers say. Getty Images/iStockphoto A wrong-way driver on a Los Angeles highway died ...

Authorities are investigating after a pedestrian was struck and killed by a vehicle on the 110 Freeway in central L.A. Saturday. California Highway Patrol officers responded to reports of a pedestrian ...